Pages tagged with Nerve Trunks Disorders

The clinical diagnosis of leprosy should always be confirmed by the laboratory tests, before starting treatment, in view of the socio-economic and psychological implications. Education of the patient on the nature of the disease, outcome of treatment, and measures to avoid spread are ...
Diagnosis of lepromatous leprosy is confirmed by the demonstration of M. leprae in the skin. A skin slit smear is prepared from the ear lobe or other areas by scraping the subepidermal tissue through a small incision. The material is stained by modified Ziehl Neelsen method.
In this form, the clinical picture truly reflects the absence of localization seen in histology. Skin lesions are numerous, which are asymmetrical, varying in size and shape. The flat lesions are not so well defined as in tuberculoid leprosy.
Leprosy, clinically and physically presents itself in various forms. At an early stage, it presents as indeterminate leprosy, but as the disease advances, it presents as Tuberculoid and Lepromatous Leprosy. A special type know as Lucio Leprosy could also manifest.
The organisms multiply in the nervous tissue, skin and upper respiratory tract mucosa. During the early stages of infection the clinical and histological changes are non-specific. The dermal nerve twigs show infiltration with round cells and histiocytes.
Leprosy is a chronic communicable disease caused by Mycobacterium leprae. Mainly, the nerves and skin are affected but it may also involved mucous membranes and other internal organs. Hansen identified the organism in 1868.
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